Peritoneal Dialysis and Malignancy: An Expertise With a Affected person Difficult by Gastric Carcinoma

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March 27, 2021 0 Comments

Case Experiences

. 2019 Mar 12;12:1179547619835176.

doi: 10.1177/1179547619835176.

eCollection 2019.


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Case Experiences

Tetsu Akimoto et al.

Clin Med Insights Case Rep.


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An 86-year-old man who had been handled with peritoneal dialysis for 14°months resulting from end-stage kidney illness secondary to hypertensive nephrosclerosis introduced with a latest historical past of malaise, stomach discomfort, and anorexia. An endoscopic analysis revealed an elevated, ulcerated, and friable lesion across the lesser curvature of the abdomen. The concurrent gastric biopsy specimens revealed reasonably differentiated adenocarcinoma, whereas a cytological examination of the dialysis fluid revealed clusters of malignant cells. That is the primary report illustrating a case of a Borrmann sort 3 gastric most cancers with synchronous peritoneal involvement through which the evaluation of the illness state was aided by the cytological evaluation of peritoneal effluent. A number of issues regarding this pathology are additionally mentioned.

Key phrases:

Peritoneal dialysis; adenocarcinoma; cytology; neoplasms; abdomen neoplasms.

Battle of curiosity assertion

Declaration of Conflicting Pursuits:The writer(s) declared the next potential conflicts of curiosity with respect to the analysis, authorship, and/or publication of this text: TA is affiliated with an endowed division supported by Terumo Co., Chugai Pharmaceutical Co., Ltd., and Kyowa Hakko Kirin Co., Ltd. The authors report no different conflicts of curiosity on this work.


Figure 1.

Determine 1.

The endoscopic and pathologic findings. On the higher gastrointestinal endoscopy (A), a Borrmann sort 3 lesion partially lined by whitish exudate was discovered within the lesser curvature of the abdomen. The biopsy websites on this view are indicated with asterisks. The examination of the biopsy specimen (B) revealed reasonably differentiated adenocarcinoma admixed with neoplastic cells, the cytoplasm of which was stuffed with clear vacuoles of mucin (arrowheads), displacing the cell nucleus to the periphery (hematoxylin and eosin staining). The cytological examination of the peritoneal dialysis effluent (C) revealed clusters of malignant cells (Papanicolaou staining). The size bar is indicated in every panel.

Figure 2.

Determine 2.

The outcomes of the stomach CT examination. Choose pictures of the CT scan (A, B) revealed the thickened gastric wall (asterisks) and enlarged lymph nodes (slender arrow) alongside the lesser curvature to the antrum of the abdomen. A nodular delicate tissue lesion within the omentum (arrowhead) and enhanced peritoneal thickening (center arrows) had been additionally confirmed. The PD catheter inside the wall of the stomach is indicated (large arrow). CT signifies computed tomography; PD, peritoneal dialysis.

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